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Assessment of future scientific needs for live variola virus

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National Academy Press , Washington, D.C
Smallpox -- Research., Smallpox -- Prevention., Smallpox vaccine., Virology -- Cultures and culture media., Smallpox, Smallpox -- prevention & control, Res
Other titlesLive variola virus
StatementCommittee on the Assessment of Future Scientific Needs for Live Variola Virus, Board on Global Health, Institute of Medicine.
SeriesThe compass series, Compass series (Washington, D.C.)
ContributionsInstitute of Medicine (U.S.). Committee on the Assessment of Future Scientific Needs for Live Variola Virus.
Classifications
LC ClassificationsQR201.S6 A85 1999
The Physical Object
Paginationxv, 108 p. :
ID Numbers
Open LibraryOL101217M
ISBN 100309064414
LC Control Number99216014
OCLC/WorldCa41416914

Informing that decision was Assessment of Future Scientific Needs for Variola Virus, which examines: Inthe World Health Organization (WHO) officially declared that smallpox had been eradicated. InWHO's international Ad Hoc Committee on Orthopox Virus Infections unanimously recommended destruction of the two remaining official stocks of variola virus.

Finally, the future scientific needs for live variola virus must be assessed in light of the knowledge that might be derived from studies of other orthopoxviruses, variola virus DNA clones, orthopoxvirus with one or more variola genes, replication-defective variola virus, live variola virus in tissue culture, and live variola virus in animal models.

Since this decision will be reconsidered in Maythe Institute of Medicine was asked to assess future scientific needs for live variola virus. This report is intended to serve health policymakers, medical and biological researchers, and the public as an assessment of the potential knowledge and capabilities that would be lost if live variola virus were no longer.

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Tip: press Ctrl-C or ⌘-C to copy. Size. Examines whether the sequenced variola genome, vaccinia, and monkey pox virus are adequate for future research or whether the live variola virus itself is needed to assist in the development of antiviral therapies.

This book also examines what further benefits would likely be gained through the use of variola in research and development efforts.

Suggested Citation:"2 Variola Virus and Other Orthopoxviruses."Institute of Medicine. Assessment of Future Scientific Needs for Live Variola gton, DC: The National Academies Press.

doi: / Informing that decision was Assessment of Future Scientific Needs for Variola Virus, which examines: - Whether the sequenced variola genome, vaccinia, and monkey pox virus are adequate for future research or whether the live variola virus itself is needed to assist in the development of antiviral therapies.

Suggested Citation:"10 Understanding of the Biology of Variola Virus."Institute of Medicine. Assessment of Future Scientific Needs for Live Variola gton, DC: The National Academies Press. doi: / NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.

Institute of Medicine (US) Committee on the Assessment of Future Scientific Needs for Live Variola Virus. Assessment of Future Scientific Needs for Live Variola Virus.

Washington (DC): National Academies Press (US); The term "detection" is used here to denote identification of the virus in the environment, while "diagnosis" refers to determination that the virus or pathogen has infected a human host.

The need to detect variola virus could arise as a result of experimentation with the virus under BSL-4 conditions in well controlled laboratories, but is perhaps more likely to occur as a result of. Committee on the Assessment of Future Scientific Needs for Live Variola Virus.;] -- Smallpox was a devastating disease that decimated human populations for centuries, and its eradication in was a monumental achievement for the global health community.

Since then the remaining Your Web browser is not enabled for JavaScript. Get this from a library. Live variola virus: considerations for continuing research. [Ann M Arvin; Deepali Patel; Institute of Medicine (U.S.).

Committee on the Assessment of Future Scientific Needs for Live Variola Virus.;]. Inthe committee on Assessment of Future Scientific Needs for Live Variola Virus hosted by the IOM reviewed all research conducted between and that date, and concluded that the development of medical countermeasures against smallpox remained of grand importance due the pandemic potential should VARV be released due to deliberate or Author: Nadia F.

Gallardo-Romero, Christina L. Hutson, Darin Carroll, Ashley V. Kondas, Johanna S. Salzer, S. Copies of Assessment of Future Scientific Needs for Live Variola Virus are available from the National Academies Press on the Internet at or by calling or Reporters may obtain a pre-publication copy from the Office of News and Public Information at the letterhead address (contacts listed above).

In the United States of America, the Institute of Medicine’s Committee on the Assessment of Future Scientific Needs for Live Variola Virus reviewed research sincefocusing on the use of live virus. 4 It concluded that live variola virus. Koplow, David.

"Smallpox: The Fight to Eradicate a Global Scourge. IOM(Institute of Medicine): "Live Variola Virus – committee on the assessment of future Scientific needs for live variola virus. National Academy Press; Mayo Foundation for Medical Education and Research (MFMER). October 1,   Assessment of Future Scientific Need for Live Variola Virus.

-based recommendations for measures to be taken by medical and public health professionals following the use of smallpox as a biological weapon against a civilian population. Assessment of Future Scientific Need for Live Variola by: Diagnosis and management of smallpox.

health body postpones destruction of smallpox. Medical countermeasures against the re-emergence of smallpox virus.

Medicine. Assessment of future scientific needs for live variola virus. Committee's scientific subcommittee, which the Committee approved.

Institute of Medicine report Academy of Sciences Institute of Medicine's Committee on the Assessment of Future Research Needs for Live Variola Virus,3 in the preparation of which he was the only WHO Advisory Committee on Variola Virus Research. Institute of Medicine, Assessment of Future Scientific Needs for Live Variola Virus (National Academy Press, Washington, DC, ).

Massung et al., Nature(). OpenUrl CrossRef PubMedCited by: Electronic Books: Virology Toggle facets Limit your search Format. Electronic Books ; Live variola virus: considerations for continuing research.

Published: Access: Online book.

Description Assessment of future scientific needs for live variola virus PDF

Assessment of future scientific needs for live variola virus. Published: Access: Online book. 2 Scientific review of variola virus research, – Executive summary Public health importance Smallpox is the only human disease that has been eradicated by a global vaccination campaign. This accomplishment remains one of the great triumphs of medical science.

Objectives of the program derive from a Institute of Medicine report that addressed the scientific needs for live variola virus. Progress in addressing these objectives has been peer reviewed annually by both a select committee organized by CDC and the World Health Organization (WHO) Advisory Committee on Variola Virus Research (2,3).

Assessment of Future Scientific Needs for Live Variola Virus. Institute of Medicine (US) Committee on the Assessment of Future Scientific Needs for Live Variola Virus.

Smallpox. Cleveland. Smallpox Clinical Case Definition. An illness with acute onset of fever ≥°F (°C) followed by a rash characterized by firm, deep-seated vesicles or pustules in the same stage of development without other apparent cause. Patient Evaluation Algorithm. Many rash illnesses can present with vesicles and pustules.

It is unlikely, though possible, that a patient. An explosion this week in a Russian lab, one of only two labs in the world known to store live samples of the variola virus, which causes smallpox, has raised anew questions that have been asked.

Institute of Medicine Assessment of future scientific needs for live variola virus. Washington: National Academy Press; p. WHO Advisory Committee on Variola Virus Research.

Report of a WHO meeting. WHO/CDS/CRS/ Geneva. Organization.

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;: 3. Assessment of future scientific needs for live variola virus Author: Reible Publisher: Reible © ISBN: ; Assessment of Hydrogen Energy for Sustainable Development Author: Sheffield Publisher: Sheffield © ISBN: 1.

Introduction. Smallpox is one of the oldest recorded infections of mankind. Likely, this agent, also known as variola, evolved by adaptation to humans from a rodent cowpox-like virus through an intermediate host, such as earliest descriptions of smallpox date to 10, b.

in Asia and uently, the spread of infection can be traced to Pacific Rim countries in Cited by: is also an Advisor for WHO Advisory Committee on variola virus Research ( - present), a Member of institute of Medicine Committee on Assessment of Future scientific Needs for Live variola virus (National Academies, UsA) ().

Dr Peter Roeder. Former secretary of GREP. Joined FAO in and became secretary of GREP in Earlier,File Size: KB. This committee of scientists also concluded that “the most compelling need for long-term retention of live variola virus is for the development of antiviral agents or novel vaccines to protect against a reemergence of smallpox due to accidental or intentional reemergence of variola virus.” WHO delayed destruction of the by: Smallpox and pregnancy: from eradicated disease to bioterrorist threat.

Smallpox, The Kothari Book Depot, Bombay, India () Google Scholar. Institute of Medicine. Assessment of future scientific needs for live variola virus, National Academy Press, Washington, DC Cited by: Variola virus. Variola virus (or variola major virus) is the virus that causes virus is one of the members of the poxvirus group (Family Poxviridae).The virus particle is brick shaped and contains a double strand of deoxyribonucleic variola virus is among the most dangerous of all the potential biological weapons.